Search results for "PsyArXiv|Neuroscience|Behavioral Neuroscience"
showing 10 items of 8055 documents
Cortical Patterns of Pleasurable Musical Chills Revealed by High-Density EEG
2020
Music has the capacity to elicit strong positive feelings in humans by activating the brain’s reward system. Because group emotional dynamics is a central concern of social neurosciences, the study of emotion in natural/ecological conditions is gaining interest. This study aimed to show that high-density EEG (HD-EEG) is able to reveal patterns of cerebral activities previously identified by fMRI or PET scans when the subject experiences pleasurable musical chills. We used HD-EEG to record participants (11 female, 7 male) while listening to their favorite pleasurable chill-inducing musical excerpts; they reported their subjective emotional state from low pleasure up to chills. HD-EEG results…
Validation study of Italian version of inventory for déjà vu experiences assessment (I-IDEA): A screening tool to detect déjà vu phenomenon in Italia…
2017
The Inventory Déjà Vu Experiences Assessment (IDEA) is the only screening instrument proposed to evaluate the Déjà vu (DV) experience. Here, we intended to validate the Italian version of IDEA (I-IDEA) and at the same time to investigate the incidence and subjective qualities of the DV phenomenon in healthy Italian adult individuals on basis of an Italian multicentre observational study. In this study, we report normative data on the I-IDEA, collected on a sample of 542 Italian healthy subjects aging between 18-70 years (average age: 40) with a formal educational from 1-19 years. From September 2013 to March 2016, we recruited 542 healthy volunteers from 10 outpatient neurological clinics i…
Quantifying Intermodal Distraction by Emotion During Math Performance: An Electrophysiological Approach
2019
Emotionally engaging stimuli are powerful competitors for limited attention capacity. In the cognitive neuroscience laboratory, the presence of task-irrelevant emotionally arousing visual distractors prompts decreased performance and attenuated brain responses measured in concurrent visual tasks. The extent to which distraction effects occur across different sensory modalities is not yet established, however. Here, we examined the extent and time course of competition between a naturalistic distractor sound and a visual task stimulus, using dense-array electroencephalography (EEG) recordings from 20 college students. Steady-state visual evoked potentials (ssVEPs) were quantified from EEG, e…
Reliability and validity of a new accelerometer-based device for detecting physical activities and energy expenditure.
2018
Background Objective assessments of sedentary behavior and physical activity (PA) by using accelerometer-based wearable devices are ever expanding, given their importance in the global context of health maintenance. This study aimed to determine the reliability and validity of a new accelerometer-based analyzer (Fibion) for detecting different PAs and estimating energy expenditure (EE) during a simulated free-living day. Methods The study consisted of two parts: a reliability (n = 18) and a validity (n = 19) test. Reliability was assessed by a 45 min protocol of repeated sitting, standing, and walking (i.e., 3 × 15 min, repeated twice), using both Fibion and ActiGraph. Validity was assesse…
The vaccinaTion & Hpv Knowledge (THinK) questionnaire: a reliability and validity study on a sample of women living in Sicily (southern-Italy)
2019
Objective The aim of this study was to introduce the VaccinaTion & Hpv Knowledge (THinK) questionnaire to assess knowledge about human papillomavirus (HPV) and attitude to HPV-vaccination. Its reliability and validity was demonstrated in a sample of women living in Sicily (southern Italy). Methods A cross-sectional survey was conducted on a sample of 220 women at the “Paolo Giaccone” University Hospital in Palermo (Sicily), aged 18–61. Data were analyzed through Cronbach’s alpha and exploratory factor analysis, followed by a structural equation model with measurement component. The two-level data structure was explicitly considered. Results Three dimensions were found: “knowledge of HP…
Psychiatric Problems in Adolescence Mediate the Association Between Childhood Learning Disabilities and Later Well-Being
2021
This follow-up study investigated the associations of childhood learning disabilities (LDs) with adult-age anxiety, depression, and unemployment. Psychosocial problems in childhood and psychiatric diagnoses and lack of education in adolescence were studied as potential mediators, and gender and mother’s education were studied as potential moderators of these associations. Data on childhood clinical neuropsychological assessments and lifelong register data on individuals with childhood LD ( n = 430; 301 [70%] males; 20–39 years of age) and matched controls ( n = 2,149) were applied. Mediation analyses were performed using structural equation modeling. Childhood LDs exerted a significant, bu…
Recognition of rapid-eye-movement sleep from single-channel EEG data by artificial neural networks: a study in depressive patients with and without a…
1996
An automatic procedure for the online recognition of REM sleep appears to be a necessary tool for selective REM sleep deprivation in depressive patients. To develop such a procedure we applied an artificial neural network to preprocessed single-channel EEG activity. EOG and EMG information was purposely not provided as input to the network. A generalized back-propagation algorithm was used for computer simulation. The sleep profile scored manually according to Rechtschaffen and Kales served as the desired output during the training period and as standard for the judgement of the network output during working mode. Polysomnographic recordings from 5 healthy subjects were pooled to train the …
α-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation
2009
The Swedish mutation within the amyloid precursor protein (APP) causes early-onset Alzheimer's disease due to increased cleavage of APP by BACE1. While beta-secretase shedding of Swedish APP (APPswe) largely results from an activity localized in the late secretory pathway, cleavage of wild-type APP occurs mainly in endocytic compartments. However, we show that liberation of Abeta from APPswe is still dependent on functional internalization from the cell surface. Inspite the unchanged overall beta-secretase cleaved soluble APP released from APP(swe) secretion, mutations of the APPswe internalization motif strongly reduced C99 levels and substantially decreased Abeta secretion. We point out t…
Depression subtyping based on evolutionary psychiatry: Proximate mechanisms and ultimate functions
2018
Major depressive disorder constitutes one of the leading causes of disability worldwide. However, it is not a unitary disease-it is a heterogeneous syndrome, with patients differing remarkably in symptom profile, pathophysiology and treatment responsiveness. Previous attempts to subtype major depressive disorder have showed limited clinical applicability. We present a classification of major depressive disorder episodes based on the proximate mechanisms that led to the original mood change that caused the depressive episode. We identify discrete depression subtypes that are induced by: 1) infection, 2) long-term stress, 3) loneliness, 4) traumatic experience, 5) hierarchy conflict, 6) grief…
EEG Data Quality: Determinants and Impact in a Multicenter Study of Children, Adolescents, and Adults with Attention-Deficit/Hyperactivity Disorder (…
2021
Electroencephalography (EEG) represents a widely established method for assessing altered and typically developing brain function. However, systematic studies on EEG data quality, its correlates, and consequences are scarce. To address this research gap, the current study focused on the percentage of artifact-free segments after standard EEG pre-processing as a data quality index. We analyzed participant-related and methodological influences, and validity by replicating landmark EEG effects. Further, effects of data quality on spectral power analyses beyond participant-related characteristics were explored. EEG data from a multicenter ADHD-cohort (age range 6 to 45 years), and a non-ADHD sc…